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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9488740376e2b15308d08237a2c60a7873b3f158e7cd4a70d21b7c3095c2ad1a' 
  AND token = 'stdUEjOFfeT6Y3L6/E1RKPF/+pKEmJPv4Yg4TTQJVSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}