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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad5c23a36e8b89409bcc5735eec2e7834e485837747a53f68268da26aa16a18' 
  AND token = 'gGeAYx8z7vtAaVpuES9NUMGwpb4lHC74ru4WaaSJPGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}