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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ab48fea41486bf43584b2f9d14be39f6baf1953b89afea9bec3ba3c5a0088c7' 
  AND token = 'npA6E5pP/cN+6CKeGnFBikuNA6Xz2B0db4DcC2SyZPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}