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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea457b87332159b0406d5f4c6f6c8b282c70503df8f8f73e4957f459fa6ab40' 
  AND token = '30D1z7h2fmXmXBIOcVMu4eyI84qN8cfl8NdAQQocg/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}