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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25856e142c8d273ba9a5765a633549d39e7e9cf7ead531bae57a4b9f4009dbd1' 
  AND token = 'ODYEXX/eo3xDK6GBkk1cuwO92rahheUCC6+WDdMWlh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}