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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b81b59f55e0edced36e692b2ab0046683ac90a6a9d06bf772834123a0f87b2' 
  AND token = '2GXr9d0FdLMBjPUTzxCKN1M/UpxDHwoVmhbr1nyTrFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}