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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f1c979198ce6deac55cfd73cde6b43b61edbcbaedb9cd839b14b6ca6725b23' 
  AND token = '0PU3SYd79UKHItEgtsVwAXpJGfN22sKzKNGW1M34+UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}