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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ff29932c1d3f46c9f90cfe831b37e6345d1c2f2b18ed1e3611d39177737f89' 
  AND token = '26/bTeqGL9yYwwmKQz6P+c13ooCv3xQuoQQpHZSXm/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}