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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22982eb0cbb1adb3270b9492418e272fecce0784123f0d111d85c95027030bd7' 
  AND token = '3mksX/tPP7VrCMe7joY997/xM5TGyCiqCOfOZk897zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}