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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e776663c028343d487582338ed94379a70e1f45c6c96cb41f0469a38a5cf77' 
  AND token = 'OCngcve3h0EYm1mPbT2uHGScODbXFzOH6uEAdbYxUOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}