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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e453fbf0d231baadd2429f31d6d6c16118f9e2cfe089134cac2ff277d54c1fe6' 
  AND token = 'Jvi+It1dBsntfaAmuLR5eYOFvtXL+5HSQCg3EfJah0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}