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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed871eb74f8cc8ef416c796898fa1b47c35eaf9334bc78a70fdee96b1aea720' 
  AND token = '+ht78S4lrV3V6avcZ08HTUFjXq8TytmQXyCMWOpFtfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}