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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954a175c9cc1d9d3bb865e94cbc55c2e2f589c1eeb14f94fd1737f45777a0264' 
  AND token = 'PFwUELcrGwTeVh8EuQ9P1fpE0CcjvxEOOYSfPay0Zpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}