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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e2ecb6a42a758b571b0f96d659fd235ce15ff049081ad924b6bb5b1bb34253' 
  AND token = 'fDLgCe3NN2fvaxK6/ZLbcxexNde5Hi75I0D2PryuZTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}