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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52869bb0e1fc85f06a687932b245fd7ca1df2095047adcf498e5b6e3d071fe7' 
  AND token = 'DPDsPCEHaIu7X0akQkuxRPjScHgAfvRK6gIALy33u4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}