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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c052f7fc8edc0dfa82bfbf489c5ccea85731fda7503ce86203679626127b4d7' 
  AND token = 'tYM3wpAzBAOw+7e1YHeDYoxSw4gBJk09q2XdC287Ofs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}