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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e676e954ac1ca8f6a6e4635a1ca337103f801f8374f6738ba6fd8ef5bdddd4' 
  AND token = 'aPDasu4IUM10bOHCfImHeiPmxFnSjIoVY8g+ooNDpbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}