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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed63cf00afc324b30c40f00b7d2af026c6739fea7abd465fc9e7d8f76f7e1287' 
  AND token = 'o+8s2ytPrJrf7nWIxoy4qrnz8YtkKc1wR2mp1CyCm4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}