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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4946a214bb131119d9b9edb368b11f6ed9d66aaddb0a149bb2063bc7cb6c2695' 
  AND token = 'TL8iRJcRJjwYMUEykhVuAR+DVe1EdQBiN1nOW6oUBBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}