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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bfb55dfc245611e2718bc28892811514e08bc90ed090943c0957180ab3a1d0' 
  AND token = '8EpHKvcfA723izDI3YG5gVA+1g34bjhw9utbzUYl2LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}