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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96e1888ed21526d4c664a5668ac6a7a526bf01fd4cc5851ac7b22d02678b4049' 
  AND token = 'qGOjBA2N5OxK9K6POgbWIOYZOaw+gp12gVcO+doAd90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}