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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aac412c37a6132d554ab567a61a03fbaa0ecef6b4c9b52f8e82341aad42777d' 
  AND token = 'NFYHC0c0Ra8Wp93dnQwty3pJgj1+Q3OyZlzAZdYISfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}