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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69fabc55a06b6cb94e12b97d32b186e1f496b60e69a1ffbd8f94444b29d39fba' 
  AND token = 'F98lRayAlzb9aCWVXc+jH+YK5YQfW8fLbGMYMY2zyu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}