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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f25be95ff3f79fb57d04bc5494c1a8b00c93d983e78f68e91ca49e4edde2368' 
  AND token = 'RQH7yKJsPMtSyfwi2ISafKL6qIN1h63GIq664BwM0Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}