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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18ba424cb6e0112b272b400ff3f69d12e5d587fb875c039ae41aa21305adaf5' 
  AND token = 'iVOPS59XaYx5lJeQ51p4l9BgyYciKaZ1+farq62QZbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}