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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38611d2b9048c3360c59a79cc10d48960155365ce3cb745cd8d174b6c6490c66' 
  AND token = 'RHGCQ858RaUSWhTiUXpwK96lFko8tAV6m+rne+lSwfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}