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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cce7a7cade17e6bb2cc75113ae08f1f99d1337f4571233a2634b3274f6ffc628' 
  AND token = 'XlWTxYyxVWXFyEFmGJenbgMS7v/E98J2UjYXJAttZlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}