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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7278500fb6858a4b4a8404c8219a0e5095ee7e9f1495ab13ca328638ed2ae3a7' 
  AND token = 'l9z6WWQDwWC3fT5u0h93sSnxP1HydbgZukxMDUlPuDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}