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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68aa5417feed8b366aa4dcbc453321ef8228000b2d496db9ce4905313eb1745c' 
  AND token = 'mGHYCGu3m4h+nOa5IOXEC/RT2sJD/4maKRfIS5be/00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}