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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0f6b8e57037a1b60e6590c7963e1ee0e6c27144314ed0649363ed292818ca4' 
  AND token = 'WvlaKDQeDG7xRBPEK7+NYbIjC5sg8VGdZ+T6mFsGHkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}