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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153de5aef44d121a352379af3b216b9cf807d13c7f575c95b617d94d1f87e302' 
  AND token = 'WQ7gM9SxtECOD1etp/aUyGmTh370qMGTG9vnR5fgLA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}