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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e22e509f570ef121ee75880b36bced8e71e1f469b1504bb66f7e0961b5a6777' 
  AND token = 'Rijx24FxHZWIleAVENpJ1n9wop7pJHlu6VOR8JEBhLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}