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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d69f7a39d5f0131bb5cc65a00330502af2f4a183af9c74ceb9bdc136114bbfb' 
  AND token = '26VnTz2I+6PRydUSI8CP1jCPzPSTZti2ufFGkMFKH4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}