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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe46e5c58749241eaded19ddde00eb323c5e0374130a4941cef68cd6a73cfa28' 
  AND token = '0PQIPjvlDJaxPXzrwLE2SZk8KoKhJ8l477Zw6r6TXsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}