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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef12b8d2091950f3a06032714693cb54d9eb53d23392d699d322bdf28e3dcd78' 
  AND token = 'YpDTbVHRcqruvjwr/W3si8Y3G80sTf/FL1XEt3bSMq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}