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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03781409f0c27cb45deb28744aa249609262d1c1617f04a2beb5f156e2155bd' 
  AND token = '1drlM/Sn3D+q98/Kn8sUzonlOjXBIEmKcQ5pS5uQJFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}