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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279e8241377227b7084b1528f02f9ad79336bb3a1f4702c39bd38e61b765da46' 
  AND token = 'h8aYpq6drEUP5peMlb9N5Gv0NnfikZyp6f52Z26+EuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}