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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac9035f132a34ca1a113e4edf09e8d088a5a92b91da35e27a2345b54b8234ac' 
  AND token = 'sxi3exd+IRE6Fx0cj/aYZFSbDTybyjvzoVDtrnvhkkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}