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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e898eb0a2327a84eb8089aa3c9d330e1fed86465d7143214a628d20b62451cf' 
  AND token = 's3KuCqNHqOZ3n3m14dkdAqOZiWruksDQi9NB/oqNeVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}