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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd02cd36c4cc166a6599e2c165bff94f2711630df2cbbcbe555a2e660af4d65f0' 
  AND token = 'qpCvX1aN2Ow9GC0APtPFOgDmHhNxDdPo45hUVRhnRZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}