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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8157293df3b16bea2be5649d264ab834f19582cb82fb857f2ce1b2de175f3cdf' 
  AND token = 'PNdmM+ssyqpJAh9H10aa9BreUvySxwJ/7uLvL2WrvZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}