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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57947aa4428263982976f13b4d008f8b781cbcdb8facb5c43f288578901038b5' 
  AND token = 'JopYiC2+SGKtWKSEtf15++8mqCePTff65eTtu2dGAx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}