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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac52e4d62bb30270266006dd5811485a51148e227640e91c7b1c2de73fe45835' 
  AND token = '2Yf28iTcJTqnRXcXVTo2K2SJR6mnUYIcLHcw9NPeTYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}