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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d79e28b7bc9355fa674c062a201e9977cbee4f3117c4b29d1f3dda37b5155a' 
  AND token = 'kDmJtUZD9QaqV4Fxs4vRYpi3da3gBdvYN8vRhp9J0KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}