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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860dc23ca429a6b6f1ae308e0472f36aaac24e2cb01218b15bc236b25ed33939' 
  AND token = '43o5xJI8nbxvrOrr4/j7ogEbUrdW4zNWqzwTyLp8Nn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}