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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e435a6dd3def2ec6314cbf28724553a37311c598a28365fd017712ccddf89d6f' 
  AND token = '9eDQ17jYP/Gj9YT5P2SbA8FLrkTzKhejn1i5vwfxWyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}