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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f686f1aa2f0eb826e8ad4ce74e51ba838ab2c5187b0e94f86f05e639d5bae216' 
  AND token = 'On16gHY6hH9k1rmjq4693kIfdh9aVZz6GwvaIJFu2tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}