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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59df9a4dd50d63551e5de5102299208e228c2c32b20475971f2f0964f7b05092' 
  AND token = 'p39j2u8TxRHPptMn6HEK8ucg/JwzLz5BV7B7OwGw6cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}