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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a570de4d047975f942b6cbda666563f4027ed10e215e7004aa130395e4cd9874' 
  AND token = 'UaXP9CgjEcQUJfxvYRU6+HK4QWFkuuX/uJA5iOr0mvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}