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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d9794c6f567a56a1b5157eb8cbd04eb1bface39860975db8ad5bbd6ecb3662' 
  AND token = 'Rf82Q2e5PKBsSAu7QLYIEvCAQJE1O+ckk2xXtGniooE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}